Our Founder

Respiratory Analytix is led by Nigel Clayton, a stalwart in the field of respiratory physiology with over 40 years of experience. 

Nigel Clayton

“At Respiratory Analytix, our journey is fueled by a sincere commitment to elevate standards in respiratory health. We firmly believe in providing nothing but the best for every individual’s respiratory well-being. Our mission revolves around empowering healthcare professionals with the expertise to deliver unparalleled respiratory care. By doing so, we contribute to healthier and happier patients. This unwavering dedication is what propels us forward each day.”

Track Record

Nigel’s track record exemplifies a wealth of expertise and accomplishments, and his career has been defined by an illustrious tenure of well over four decades in Respiratory Physiology. With a proven history of leadership and impactful contributions to the field, Nigel stands as a trailblazer in advancing our understanding of respiratory health and enhancing the quality of care provided to individuals worldwide.

  • Over four decades of expertise in Respiratory Physiology, including 35 years overseeing the Respiratory Physiology department at Wythenshawe Hospital’s Northwest Lung Centre.
  • Respiratory technical assessor on behalf of the United Kingdom Accreditation Service (UKAS).
  • Respiratory Clinical Tutor for BSc and MSc courses in Respiratory Clinical Physiology at Manchester Metropolitan University. This role involved curriculum design, lectures, examination setting, and clinical placements supervision, since 1981.
  • Recognition by the European Respiratory Society as a registered spirometry trainer from 2012.
  • Examiner and facilitator for ARTP spirometry and professional body exams since 1998.
  • Independent expert for pharmaceutical companies, offering spirometry and lung function training to sites in international drug studies. Nigel provides invaluable pre-study data analysis, expert over-reading of lung function data, and on-site and remote training in numerous countries worldwide.
  • Chair for ARTP manufacturers’ liaison from 1998 to 2018 and deputy chair for UK standards in Respiratory Physiology from 2014 to 2018.
  • Registration with the Registration Council for Clinical Physiology.
  • Extensive published work (see below).


Nigel’s multifaceted contributions underscore his status as a respected authority, shaping the future of respiratory care and education.

Decades of Expertise

Including managing Respiratory Physiology departments and teaching at reputable universities.

International Recognition

Recognised by the European Respiratory Society and the Association for Respiratory Technology and Physiology.

Industry Publications

Contributed to prestigious journals, including the European Respiratory Journal and Chronic Respiratory Disease.

Unmatched Track Record

Proven track record in delivering ARTP-accredited spirometry training and examinations over 15 years.

Media Appearances

Nigel’s contributions to respiratory physiology have led to appearances on several television programmes, including Tonight With Trevor McDonald and Channel 4 News. These platforms have enabled him to share his insights and knowledge, making complex respiratory topics accessible to a broader audience.

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Apetroaei, S. A., Clayton, N., & Dowding, D. (2021). Cardio-respiratory exercise, incremental shuttle walk test and thoracoscore in predicting outcomes following thoracotomy. Thorax76(1). https://thorax.bmj.com/content/76/Suppl_1/A13.1

Sylvester, K.P., Clayton, N., Cliff, I.et al. (2020). ARTP statement on pulmonary function testing. BMJ Open Respiratory Research. https://bmjopenrespres.bmj.com/content/7/1/e000575.info

Driskel, M., Horsley, A., Fretwell, N., Clayton, N., & Al-Aloul, M. (2019). Lung clearance index in detection of post-transplant bronchiolitis obliterans syndrome. ERJ Open Research5(4).

Sprigings, D., Jeffrey, A., Barber, P., & Clayton, N. (2018). Chronic breathlessness. In P. Davey, D. Sprigings, P. Davey, & D. Sprigings (Eds.), Diagnosis and Treatment in Internal Medicine pp. 51-55. Oxford University Press. https://doi.org/10.1093/med/9780199568741.003.0013

Driskel, M., Horsley, A., Clayton, N., & Al-Aloul, M. (2018). S111 Lung clearance index (LCI) Is a sensitive marker of bronchiolitis obliterans syndrome (BOS) post lung transplant (LTX). Thorax73(Suppl 4) A69-A70. https://thorax.bmj.com/content/73/Suppl_4/A69.info

Sharman, A., Pate, L., Clayton, N., Culshaw, C., Santhanakrishan, K., Sutcliffe, R., Newton, H., Nuttall, J., Leonard, C., & Al-Aloul, M. (2017). CT derived estimates of Total Lung volume in Transplant candidates. Can we do without plethysmography? The Journal of Heart and Lung Transplantation36(4), S404-S405.

Al-Najjar, H., Evison, M., Clayton, N., Crosbie, P., Shah, R., & Booton, R. (2015). Physiological assessment in thoracic surgery for high-risk patients with lung cancer; how do international guidelines compare? Journal of Thoratic Oncology10(9), S437-S437.

Gupta, S., Waywell, C., Gandhi, N., Clayton, N., Keevil, B., Clark, A. L., Ng, L. L., Brooks, N., & Neyses, L. (2010). The effects of adding torasemide to standard therapy on peak oxygen consumption, natriuretic peptides, and quality of life in patients with compensated left ventricular systolic dysfunction. European Journal of Heart Failure12(7), 746-752.

Prys-Picard, C., Schofield, M., Clayton, N., & Niven, R. (2008). The restrictive physiology in patients with severe asthma due to tidal breathing at residual volume; A form of dysfunctional breathing. American Thoracic Society Conference.

Clayton, N. (2007). Lung function made easy: Assessing lung size. Chronic Respiratory Disease4, 151-157. https://journals.sagepub.com/doi/pdf/10.1177/1479972307081647

Gupta, S., Gandhi, N., Waywell, C., Clayton, N., Coppinger, T., Ng, L. L., Brooks, N., & Neyses., L. (2007). The effect of introducing diuretics in compensated patients with left ventricular dysfunction on quality of life, plasma BNP levels, NBNB levels and peak oxygen consumption: Results from a double blind placebo controlled cross-over study. British Cardiovascular Society Annual Scientific Conference. Glasgow.

Fox, D. J., Khattar, R. S., Fitzpatrick, A. P., Borg, A. N., Clayton, N., Beynon, R. P., Williams, S. G., Khan, W., Shaw, S., M., Roberts, S. A., & Davidson N. (2007). Echocardiographic optimisation of inter-ventricular delay improves exercise performance compared to simultaneous biventricular pacing. British Cardiovascular Society Annual Scientific Conference. Glasgow.

Fox, D., Fitzpatrick, A., Borg, A., Khattar, R., Williams, S., Clayton, N., Beynon, R., & Davidson, N. (2006). Reduction in B-Type natriuretic peptide levels in CRT patients predicts an improvement in peak oxygen consumption. American Heart Association Annual Conference.

Fox, D., Fitzpatrick, A., Williams, S., Khattar, R., Borg, A., Clayton, N., & Davidson, N. (2006). Effect of sequential versus simultaneous cardiac resynchronization therapy upon peak oxygen consumption. British Cardiac Society. Glasgow.

Gupta, S., Gandhi, N., Clayton, N., Waywell, C., Coppinger, T., Brooks, N. & H., Neyses, L. (2006). The effect of diuretics on peak oxygen consumption and quality of life in patients with compensated left ventricular dysfunction. BCS Annual Scientific Conference.

Gupta, S., Gandhi, N., Clayton, N., Waywell, C., Coppinger, T., Brooks, N. & H., Neyses, L. (2006). The effect of diuretics on peak oxygen consumption in patients with compensated left ventricular dysfunction. British Cardiac Society. Glasgow.

Clayton, N. (2005). Whole body plethysmography. In B. Cooper, A. Evans, A. Kendrick, & C. Newall (Eds.), ARTP Practical Handbook of Respiratory Function Testing – Part Two (2nd ed., pp. 260-274). Association for Respiratory Technology and Physiology.

Clayton, N. (2003). Static lung volumes and capacities. In B. Cooper, A. Evans, A. Kendrick, & C. Newall (Eds.), Practical handbook of Respiratory Function Testing – Part One (2nd ed., pp.177-198). Association for Respiratory Technology and Physiology.

Moloney, E. D., Clayton, N., Mukherjee, D. K., Gallagher, C. G., & Egan, J. J. (2003). The shuttle walk exercise test in idiopathic pulmonary fibrosis. Respiratory Medicine97(6), 682-687. https://doi.org/10.1053/rmed.2003.1501

Convery, R. P., Jack, S., Whabi, Z., Clayton, N., Egan, J. J., Warburton, C., & Earis, J. E. (2002). Impulse oscillometry (IOS) in the diagnosis and management of obliterative bronchiolitis (OB) following lung transplantation. European Respiratory Society.

Negro, R. D., Micheletto, C., Tognella, S., Clayton, N., Cantini, L., & Woodcock, A. (2001). Evidence of adequacy of the performance of the pulvinal by measuring through-device Peak inspiratory flow rate in severe airways obstruction in adults and children. Journal of Aerosol Medicine14(3), 343-349. https://doi.org/10.1089/089426801316970303

Mukherjee, D., Clayton, N., & Egan, J. J. (2000). Shuttle walk test and VO2 Max in idiopathic pulmonary fibrosis (IPF). European Respiratory Society.

Dodd, M. E., Moorcroft, A. J., Haworth, C. S., Francis, S., Miles, J., & Clayton, N. (2000). The effect of rhDNase on exercise performance and gas trapping in adults with cystic fibrosis: a randomised controlled trial. In 13th International Cystic Fibrosis Congress (pp. 4-8).

Clayton, N., Cantini, L., & Woodcock, A. A. (1999). Ability to use dry powder inhalers is unrelated to severity of expiratory airflow obstruction. American Thoracic Society Conference. San Diego.

Clayton, N., Collyns, T., Egan, J., Isalska, B., Standbridge, T., & Woolcock, A. (1995). Evaluation of effectiveness of four bacterial filters during pulmonary function testing. Thorax50(Suppl 2), 65.

Taskar, V., Clayton, N., Atkins, M., Shaheen, Z., Stone, P., & Woodcock, A. (1995). Breath-holding Time in Normal Subjects, snorers, and sleep apnea patients. Chest107(4), 959-962. https://doi.org/10.1378/chest.107.4.959

Atkins, M., Taskar, V., Clayton, N., Stone, P., & Woodcock, A. (1994). Nasal resistance in obstructive sleep apnea. Chest105(4), 1133-1135. https://doi.org/10.1378/chest.105.4.1133


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